BDBM50380144 CHEMBL2010994::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 8
SMILES CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(cc2)S(N)(=O)=O)n1
InChI Key InChIKey=OMYTZYUGUKDESE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50380144
Affinity DataKoff: 2.50E+5s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 4.90E+5s-1Assay Description:Binding affinity to human recombinant CA7 assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 51nMAssay Description:Binding affinity to human recombinant CA7 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human recombinant CA7 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0250M-1s-1Assay Description:Binding affinity to human recombinant CA7 assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-7 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-7 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0100M-1s-1Assay Description:Binding affinity to CA7 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.230nMAssay Description:Binding affinity to CA7 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair